June 2021 – Caring for a loved one who is up all night is not sustainable.
Using a low-dose stimulant, like methylphenidate, in the daytime to treat apathy and daytime drowsiness has helped patients normalize sleep patterns in case reports.
We use methylphenidate to treat end-of-life fatigue successfully in select patients. This is a new application to consider.
A starting dose of immediate-release methylphenidate 2.5 mg in the morning and early afternoon is well tolerated by our patients.
Titrating up as tolerated and changing to long-acting formulation is recommended if effective.